drugset / Trial / NCT05102721

Trial of Immunotherapy With Avelumab and Pepinemab As Second Line For Patients With Metastatic Pancreatic Adenocarcinoma

NCT05102721

Phase 1/2 Active not recruiting 48 enrolled Vaccinex Inc. University of Rochester · collab
NaSequentialOpen-labelTreatment

Summary

This trial will assess the safety and tolerability of Pepinemab in combination with Avelumab in patients with metastatic pancreatic adenocarcinoma that has progressed after first line chemotherapy. Phase 2 will assess the efficacy of this combination therapy.

Timeline

Start
2022-12-10
Primary completion
2028-12-31
Completion
2028-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Avelumab Monoclonal antibody Intravenous
Subject Pepinemab Monoclonal antibody Intravenous