Study to Evaluate the Safety and Efficacy of ASC40 in Subjects With Moderate to Severe Acne Vulgaris

Summary

This is a phase2, randomized, double-blind, multi-center, multi-dose and placebo parallel controlled design. The subjects in the study group were given double-blind drugs, and they were taken (orally) after dinner every day according to the requirements of clinical trial scheme.

Timeline

Start

2022-01-12

Primary completion

2023-04-10

Completion

2023-04-10

Publications

• Chen Q, Chen R, Wu L, Xu A, He L, Wang J, Lu Y, Xiao R, Liu L, Feng Y, Zhang C, Dai X, Gao Y, Yan Y, Wu JJ, Xiang L. Denifanstat for moderate-to-severe acne: A Phase 2, randomized, double-blind, placebo-controlled trial. J Eur Acad Dermatol Venereol. 2026 Jul;40(7):1238-1246. doi: 10.1111/jdv.70119. Epub 2025 Nov 4.

Drugs

Indications