drugset / Trial / NCT05104801

Sitravatinib With or Without Tislelizumab in Patients With Unresectable or Metastatic Melanoma

NCT05104801

Phase 2 Unknown 37 enrolled Peking University Cancer Hospital & Institute
RandomizedParallel-groupOpen-labelTreatment

Summary

In 2014, an estimated 7,000 patients were diagnosed of melanoma in China. It is growing at an annual rate of 3%-5% and approximately 20,000 new cases are reported each year recently.To date, CFDA only approved dacarbazine as first line chemotherapy and anti-PD-1 antibody monotherapy as second line. There is no standard of care after chemotherapy and anti-PD-1.

Timeline

Start
2021-11
Primary completion
2023-09
Completion
2023-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Sitravatinib Small molecule 100 mg Oral
Subject Tislelizumab Monoclonal antibody 200 mg Intravenous

Indications