drugset / Trial / NCT05104801
Sitravatinib With or Without Tislelizumab in Patients With Unresectable or Metastatic Melanoma
RandomizedParallel-groupOpen-labelTreatment
Summary
In 2014, an estimated 7,000 patients were diagnosed of melanoma in China. It is growing at an annual rate of 3%-5% and approximately 20,000 new cases are reported each year recently.To date, CFDA only approved dacarbazine as first line chemotherapy and anti-PD-1 antibody monotherapy as second line. There is no standard of care after chemotherapy and anti-PD-1.
Timeline
- Start
- 2021-11
- Primary completion
- 2023-09
- Completion
- 2023-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Sitravatinib | Small molecule | 100 mg | Oral |
| Subject | Tislelizumab | Monoclonal antibody | 200 mg | Intravenous |