drugset / Trial / NCT05108818
Characterization of Humoral and Cellular Immune Responses Elicited by Influenza Vaccination in Healthy Adults
Phase 4
Recruiting
700 enrolled
University of Pennsylvania
National Institute of Allergy and Infectious Diseases (NIAID) · collabStanford University · collabThe Scripps Research Institute · collab
NaSingle-groupOpen-labelBasic science
Summary
Cellular and humoral immune responses before and after seasonal influenza vaccination will be assessed. Each year, up to 100 participants will be enrolled. To study age-specific differences in immune responses, participants with various years of birth will be enrolled. The investigators hypothesize that humans with different birth years will mount antibody and cellular responses of different specificities following seasonal influenza vaccination.
Timeline
- Start
- 2021-10-07
- Primary completion
- 2027-04-01
- Completion
- 2028-03-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Quadrivalent influenza vaccine | Vaccine | 15 ug | Intramuscular |