drugset / Trial / NCT05110144

Efficacy of Two Doses of Duloxetine and Amitriptyline in Subjects With Refractory Chronic Cough

NCT05110144

Phase 2 Recruiting 50 enrolled Mayo Clinic
RandomizedParallel-groupQuadruple-blindTreatment

Summary

This research study is evaluating the effectiveness of escalating doses of Amitriptyline and Duloxetine in reducing cough frequency in patients with refractory chronic cough (RCC)

Timeline

Start
2021-11-01
Primary completion
2026-12
Completion
2026-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Amitriptyline Small molecule 25 mg Oral
Subject Amitriptyline Small molecule 50 mg Oral
Subject Duloxetine Small molecule 30 mg Oral
Subject Duloxetine Small molecule 60 mg Oral

Indications

No indication recorded.