Reversal of Botulinum Neurotoxin Injection Related Dysphonia With Pyridostigmine

Summary

The purpose of this study is to evaluate the effects of pyridostigmine (Mestinon) on patient vocal outcomes after undergoing laryngeal botulinum neurotoxin (BoNT) injections, which is a standard treatment for spasmodic dysphonia. Pyridostigmine (Mestinon) has been used for treatment of BoNT overdose, and it is our hope that it will be beneficial in the management of post BoNT breathy phase.

Timeline

Start

2021-05-20

Primary completion

2022-12-31

Completion

2023-06-01

Drugs

Indications