drugset / Trial / NCT05113940
A Study of PF-07258669 In Healthy Adult Participants
RandomizedSequentialDouble-blindBasic science
Summary
Part A of this study is to evaluate safety, tolerability, and pharmacokinetics (PK) of PF-07258669 after administration of multiple ascending oral doses to healthy adult participants. Optional cohorts of healthy adult Japanese participants and/or older adult participants may also be evaluated if results in other cohorts support further evaluation. Part B of this study is a 2-period, fixed-sequence, multiple-dose, open-label design to evaluate the effect of PF-07258669 on midazolam PK in healthy adult participants. Part B will be conducted if the results of Part A support further evaluation of PF-07258669.
Timeline
- Start
- 2021-11-08
- Primary completion
- 2023-07-27
- Completion
- 2023-07-27
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Midazolam | Small molecule | — | Oral |
| Subject | PF-07258669 | Unknown | — | Oral |
Indications
No indication recorded.