drugset / Trial / NCT05116085

Efficacy and Safety of Tislelizumab (BGB-A317) as Neo-Adjuvant Treatment in Participants With Colorectal Cancer

NCT05116085 ↗

Phase 2 Completed 33 enrolled BeiGene
NaSingle-groupOpen-labelTreatment

Summary

The main purpose of this study was to help meet the medical needs of people in China with certain types of solid tumors that have specific genetic changes called microsatellite instability-high (MSI-H) or deficient mismatch repair (dMMR). The study looked at how well the drug tislelizumab works and how safe it is when given before surgery (neoadjuvant treatment) for these types of tumors.

Timeline

Start
2022-01-26
Primary completion
2023-09-26
Completion
2025-01-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Tislelizumab Monoclonal antibody 200 mg Intravenous

Indications