drugset / Trial / NCT05118984

Efficacy of Azithromycin in MSAF Cases to Improve Maternal and Neonatal Outcomes

NCT05118984

Phase 4 Completed 324 enrolled Cairo University
RandomizedParallel-groupDouble-blindPrevention

Summary

Meconium stained amniotic fluid increases the risk of maternal complications (e.g., dystocia, operative delivery, and postpartum endometritis) and neonatal complications (e.g., sepsis, admission to the neonatal intensive care unit \[NICU\], and meconium aspiration syndrome). The goal of the study is to compare between Azithromycin vs Placebo in cases of meconium stained amniotic fluid during the first stage of labor in multigravida women and their effect on maternal and neonatal outcomes.

Timeline

Start
2021-02-16
Primary completion
2021-05-31
Completion
2021-10-04

Drugs

EvaluationDrugModalityDoseRoute
Comparator Azithromycin Small molecule 250 mg

Indications