drugset / Trial / NCT05120934

Efficacy of Two Doses of Duloxetine & Amitriptyline in Interstitial Lung Disease-related Cough

NCT05120934

Phase 2 Recruiting 25 enrolled Mayo Clinic
RandomizedParallel-groupQuadruple-blindTreatment

Summary

This research study is evaluating the effectiveness of escalating doses of Amitriptyline and Duloxetine in reducing cough frequency in patients with interstitial lung disease (ILD)-related cough.

Timeline

Start
2021-11-01
Primary completion
2026-10
Completion
2026-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Amitriptyline Small molecule 25 mg Oral
Subject Amitriptyline Small molecule 50 mg Oral
Subject Duloxetine Small molecule 30 mg Oral
Subject Duloxetine Small molecule 60 mg Oral