drugset / Trial / NCT05123599
A Study of JNJ-73763989, JNJ-64300535, and Nucleos(t)Ide Analogs in Virologically Suppressed, Hepatitis B e Antigen (HBeAg)- Negative Participants With Chronic Hepatitis B Virus Infection
NaSingle-groupOpen-labelTreatment
Summary
The purpose of this study is to evaluate the efficacy of the study intervention based on hepatitis B surface antigen (HBsAg) levels.
Timeline
- Start
- 2021-12-06
- Primary completion
- 2023-07-31
- Completion
- 2024-06-26
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | JNJ-64300535 | Vaccine | — | Intramuscular |
| Subject | JNJ-73763989 | Small interfering RNA (siRNA) | — | Subcutaneous |
| Background | ETV monohydrate | Unknown | — | Oral |
| Background | TAF | Unknown | — | Oral |
| Background | Tenofovir disoproxil fumarate | Small molecule | — | Oral |