drugset / Trial / NCT05127889

the Remineralizing Self-Assembling Peptide P11-4, 2% Arginine Enriched Sodium Fluoride and Functionalized Tri Calcium Phosphate Fluoride White Spot Lesions

NCT05127889

Unknown 39 enrolled Ain Shams University
RandomizedParallel-groupSingle-blindTreatment

Summary

The aim of the current study is to compare the remineralizing ability of Self-assembling peptide P11-4, 2% Arginine Enriched Sodium Fluoride and Functionalized Tri Calcium Phosphate Fluoride varnishes in treatment of white spot lesions both in-vivo and in-vitro . A) Primary Objective Assessment of: * Dimensions of the WSLs through digital photography. * The color of WSLs through spectrophotometer. B) Secondary Objectives Assessment of: • Degree of remineralization using Polarized Light Microscope.

Timeline

Start
2022-01-01
Primary completion
2023-04-02
Completion
2024-01-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Arginine-enriched Sodium Fluoride varnish Unknown Topical
Subject P11-4 Peptide Topical
Subject Tri Calcium Phosphate Fluoride varnish Unknown Topical