drugset / Trial / NCT05127889
the Remineralizing Self-Assembling Peptide P11-4, 2% Arginine Enriched Sodium Fluoride and Functionalized Tri Calcium Phosphate Fluoride White Spot Lesions
RandomizedParallel-groupSingle-blindTreatment
Summary
The aim of the current study is to compare the remineralizing ability of Self-assembling peptide P11-4, 2% Arginine Enriched Sodium Fluoride and Functionalized Tri Calcium Phosphate Fluoride varnishes in treatment of white spot lesions both in-vivo and in-vitro . A) Primary Objective Assessment of: * Dimensions of the WSLs through digital photography. * The color of WSLs through spectrophotometer. B) Secondary Objectives Assessment of: • Degree of remineralization using Polarized Light Microscope.
Timeline
- Start
- 2022-01-01
- Primary completion
- 2023-04-02
- Completion
- 2024-01-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Arginine-enriched Sodium Fluoride varnish | Unknown | — | Topical |
| Subject | P11-4 | Peptide | — | Topical |
| Subject | Tri Calcium Phosphate Fluoride varnish | Unknown | — | Topical |