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drugset / Trial / NCT05131555

Influence of Endurance Exercise and Histamine Receptors on the Gene Expression in Skeletal Muscle

NCT05131555 ↗

Completed 14 enrolled University Ghent Research Foundation Flanders · collab
RandomizedCrossoverTriple-blindBasic science

Summary

Blocking histamine H1/H2 receptors blunts chronic endurance training adaptations. The current study addresses a twofold research question: "What is the influence of endurance training (1) and histamine H1 and H2 signaling (2) on the gene expression in human skeletal muscle." Results from this study will yield more insights into the molecular mechanisms of adaptations to exercise training.

Timeline

Start
2021-08-16
Primary completion
2021-12-06
Completion
2021-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Famotidine Other / unclassified 40 mg Oral
Subject Fexofenadine Unknown 540 mg Oral

Indications

No indication recorded.