drugset / Trial / NCT05136937
A Clinical Study of Intratumoral Administration of RT-01 in Patients With Advanced Solid Tumors
NaSequentialOpen-labelTreatment
Summary
This is an open-label, dose escalation study of the safety and tolerability of oncolytic virus injection(RT-01) when administered via intratumoral injection in patients with advanced solid tumors. The purpose of this study is to assess the safety and tolerability of RT-01 and to determine the recommended phase 2 dose (RP2D) for further study. The study will also evaluate antitumor activity, objective response rate, pharmacokinetics and virus shedding of RT-01.
Timeline
- Start
- 2021-11-01
- Primary completion
- 2022-06-01
- Completion
- 2023-06-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | RT-01 | Other / unclassified | 1e+07 unknown | Other |
| Subject | RT-01 | Other / unclassified | 1e+08 unknown | Other |
| Subject | RT-01 | Other / unclassified | 7e+08 unknown | Other |