drugset / Trial / NCT05137496

Ruxolitinib and Methylprednisolone as a First-line Treatment for Macrophage Activation Syndrome

NCT05137496

Phase 3 Unknown 40 enrolled Beijing Friendship Hospital
NaSingle-groupOpen-labelTreatment

Summary

The present study was a single-center, prospective, non-comparative in which macrophage activation syndrome patients were selected as the main subjects to evaluate the effect and safety of Ruxolitinib and methylprednisolone regimens as the first-line therapy .

Timeline

Start
2022-06-01
Primary completion
2023-06-01
Completion
2024-06-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Methylprednisolone Other / unclassified 2 mg/kg
Subject Ruxolitinib Small molecule 0.3 mg/kg Intravenous