drugset / Trial / NCT05137548

A Drug-Drug Interaction Study Between ATI-2173 and Tenofovir Disoproxil Fumarate in Healthy Subjects

NCT05137548

Phase 1 Completed 32 enrolled Antios Therapeutics, Inc
Non-randomizedSequentialOpen-labelTreatment

Summary

This study is a single-center, open-label, 2-cohort, multiple dose, fixed-sequence, DDI study in healthy adult subjects. Healthy volunteers will be administered multiple oral doses of ATI-2173 in combination with tenofovir disoproxil fumarate and assessed for safety and tolerability including blood tests to show how the body metabolizes and eliminates the investigational drug as well as how the investigational drug interacts with tenofovir disoproxil fumarate.

Timeline

Start
2021-10-27
Primary completion
2021-12-23
Completion
2021-12-23

Drugs

EvaluationDrugModalityDoseRoute
Subject FOSCLEVUDINE ALAFENAMIDE Other / unclassified 50 mg Oral
Subject Tenofovir Small molecule 300 mg Oral

Indications

No indication recorded.