A Study to Evaluate Sapablursen (Formerly ISIS 702843, IONIS-TMPRSS6-LRx) in Patients With Polycythemia Vera

Summary

The main purpose of this study is to evaluate the efficacy of sapablursen in reducing the frequency of phlebotomy and in improving quality of life assessments in participants with polycythemia vera.

Timeline

Start

2021-12-30

Primary completion

2025-06-26

Completion

2026-06-02

Outcome

Met primary endpoint

release “In both cohorts, the study achieved its primary endpoint of significantly decreasing weekly phlebotomy rate” deciphera.com ↗

Drugs

Indications