drugset / Trial / NCT05144347

Study of XL114 in Subjects With Non-Hodgkin's Lymphoma

NCT05144347 ↗

Phase 1 Terminated 2 enrolled Exelixis
Non-randomizedSequentialOpen-labelTreatment

Summary

This is a Phase 1, non-randomized, open-label, dose-escalation and expansion study, evaluating the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and preliminary clinical antitumor activity of XL114 administered alone orally to subjects with Non-Hodgkin's Lymphoma (NHL). The objectives of the study also include determining the recommended dose (RD) and/or maximum tolerated dose (MTD) of XL114.

Timeline

Start
2022-04-12
Primary completion
2022-11-01
Completion
2022-11-01

Outcome

Outcome not reported

Stopped: “Due to Sponsor reasons.”

Drugs

EvaluationDrugModalityDoseRoute
Subject XL114 Unknown — Oral