drugset / Trial / NCT05146089
Reflex Responses to Intermittent Hypoxia in Humans: Mechanisms and Consequences
Phase 0
Completed
54 enrolled
University of Missouri-Columbia
Mayo Clinic · collabNational Heart, Lung, and Blood Institute (NHLBI) · collab
NaSingle-groupOpen-labelBasic science
Summary
The overall goal of this project is to better understand the effect of intermittent hypoxia (IH) on sympathetic neuronal discharge patterns in humans, as well as mechanisms that mediate persistent sympathoexcitation with IH.
Timeline
- Start
- 2016-12-20
- Primary completion
- 2018-09-08
- Completion
- 2021-04-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bosentan | Other / unclassified | 62.5 mg | Oral |