drugset / Trial / NCT05151549

A Study of Carilizumab Combined With Concurrent Chemoradiotherapy

NCT05151549 ↗

NaSingle-groupOpen-labelTreatment

Summary

This is a one-arm phase II clinical study. In patients with stage III-IVA cervical cancer with pelvic lymph nodes \> 2cm, positive para-aortic lymph nodes, or lymph node metastases \> 2, patients with positive PD-L1 expression (CPS score ≥1) were treated with cararizumab combined with conventional concurrent chemoradiotherapy and immunomaintenance therapy for one year. To evaluate the efficacy and safety of carilizumab in combination with concurrent chemoradiotherapy and subsequent maintenance therapy.

Timeline

Start
2021-12-01
Primary completion
2023-12-12
Completion
2023-12-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Camrelizumab Monoclonal antibody 200 mg Intravenous
Background Carboplatin Small molecule 2 unknown Intravenous
Background Cisplatin Other / unclassified 40 mg/m2 Intravenous

Indications