drugset / Trial / NCT05153174

Study of Sulphoraphane in Chronic Kidney Disease

NCT05153174

RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to test the safety of the compound sulforaphane that boosts the activity of antioxidant genes in the body to combat oxidative stress. Oxidative stress has been shown experimentally to play a role in kidney disease. This drug has been tested in patients with breast cancer who have normal kidney function, but has never been tested in patients with kidney disease. In this study, the investigators will establish a safe dose for patients with chronic kidney disease based on blood levels achieved in patients with normal kidney function.

Timeline

Start
2022-05-02
Primary completion
2023-05-25
Completion
2023-06-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Sulforaphane Small molecule