drugset / Trial / NCT05161936

A Study to Evaluate Lumasiran in Adults With Recurrent Calcium Oxalate Kidney Stone Disease and Elevated Urinary Oxalate Levels

NCT05161936 ↗

Phase 2 Terminated 2 enrolled Alnylam Pharmaceuticals
RandomizedParallel-groupTriple-blindTreatment

Summary

The primary purpose of this study is to evaluate the effect of lumasiran on the percent change in urinary oxalate excretion in patients with recurrent calcium oxalate kidney stone disease.

Timeline

Start
2022-01-27
Primary completion
2022-11-01
Completion
2022-11-01

Outcome

Outcome not reported

Stopped (Enrollment): “Study terminated early due to low enrollment”

Drugs

EvaluationDrugModalityDoseRoute
Subject Lumasiran Small interfering RNA (siRNA) — Subcutaneous