drugset / Trial / NCT05166811
Timely Intravenous Magnesium for Asthma in Children
Phase 2
Completed
52 enrolled
University of Utah
Children's Hospital of Philadelphia · collabNational Heart, Lung, and Blood Institute (NHLBI) · collabNationwide Children's Hospital · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
Many children currently being hospitalized with severe asthma could potentially avoid hospitalization and be sent home if their treatment in the emergency department was more effective. The investigators will conduct a pilot trial that will lead to a larger study to conclusively answer whether a simple and inexpensive medicine, intravenous magnesium sulfate, can be used in the emergency department to prevent hospitalization for these children.
Timeline
- Start
- 2022-09-12
- Primary completion
- 2023-05-31
- Completion
- 2023-07-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Magnesium Sulfate | Other / unclassified | 50 mg/kg | Intravenous |
| Comparator | Magnesium Sulfate | Other / unclassified | 75 mg/kg | Intravenous |