drugset / Trial / NCT05170555

Diagnosis of Renal Cell Carcinoma on 68Ga-PSMA PET-CT and Radioligand Therapy With 177Lu-EB-PSMA-617

NCT05170555

NaSingle-groupOpen-labelDiagnostic

Summary

Renal Cell Carcinoma (RCC) is the second most common tumor in urology. Considering its origination from kidney, an organ with intense physiological uptake and excretion of 68Ga-PSMA, this study aims to evaluate the uptake of 68Ga-PSMA in RCC compared to 18F-FDG in the same patients, and assess the feasibility of 177Lu-EB-PSMA-617 treatment in patients with the advanced RCC.

Timeline

Start
2021-12-01
Primary completion
2022-10-01
Completion
2023-07-01

Drugs

EvaluationDrugModalityDoseRoute
Subject 177Lu-EB-PSMA-617 Other / unclassified 1850 mbq Intravenous
Subject 68Ga-PSMA-11 Diagnostic / imaging agent 74 mbq Intravenous
Subject 68Ga-PSMA-11 Diagnostic / imaging agent 148 mbq Intravenous

Indications