drugset / Trial / NCT05178628
The Impact of Thromboprophylaxis on Progression Free Survival of Patients With Advanced Pancreatic Cancer
RandomizedParallel-groupOpen-labelPrevention
Summary
This is a prospective, randomized, multicenter, open-label, blinded-endpoint Phase III clinical trial to investigate the impact of thromboprophylaxis using innohep, beyond anticoagulation in the improvement of the clinical outcomes in active pancreatic cancer patients receiving systemic anti-neoplasmatic treatment. The number of patients that will be enrolled is 450. The enrollment period is 24 months and the follow up period is 10 months.
Timeline
- Start
- 2022-02-10
- Primary completion
- 2024-12-31
- Completion
- 2024-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Tinzaparin | Other / unclassified | 175 iu/kg | Subcutaneous |
| Comparator | Gemcitabine | Small molecule | — | — |
| Comparator | Paclitaxel | Small molecule | — | — |