drugset / Trial / NCT05178628

The Impact of Thromboprophylaxis on Progression Free Survival of Patients With Advanced Pancreatic Cancer

NCT05178628

Phase 3 Unknown 450 enrolled Michalis Karamouzis
RandomizedParallel-groupOpen-labelPrevention

Summary

This is a prospective, randomized, multicenter, open-label, blinded-endpoint Phase III clinical trial to investigate the impact of thromboprophylaxis using innohep, beyond anticoagulation in the improvement of the clinical outcomes in active pancreatic cancer patients receiving systemic anti-neoplasmatic treatment. The number of patients that will be enrolled is 450. The enrollment period is 24 months and the follow up period is 10 months.

Timeline

Start
2022-02-10
Primary completion
2024-12-31
Completion
2024-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Tinzaparin Other / unclassified 175 iu/kg Subcutaneous
Comparator Gemcitabine Small molecule
Comparator Paclitaxel Small molecule