drugset / Trial / NCT05182749

Safety and Efficacy of the Bacteriophage Preparation, ShigActive™, in a Human Experimental Model of Shigellosis

NCT05182749

Phase 1/2 Active not recruiting 52 enrolled Intralytix, Inc. University of Maryland, Baltimore · collab
RandomizedParallel-groupQuadruple-blindPrevention

Summary

The study is a first-in-human Phase 1/2a randomized, double-blind, placebo-controlled trial to assess the clinical safety and efficacy of ShigActive in healthy adults with experimental Shigella challenge.

Timeline

Start
2023-02-23
Primary completion
2024-12-09
Completion
2025-09-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Bacteriophage Other / unclassified 1 ml Oral

Indications