drugset / Trial / NCT05183178
Switching From Ticagrelor to Prasugrel in Patients With Acute Coronary Syndrome
Phase 4
Completed
17095 enrolled
Vastra Gotaland Region
Jämtland County Council, Sweden · collabRegion Gävleborg · collabRegion Halland · collabRegion Skane · collabRegion Västerbotten · collabRegion Örebro County · collab
RandomizedSequentialOpen-labelTreatment
Summary
This study proposes to conduct the switch from ticagrelor to prasugrel in an organized stepwise manner, to allow for the evaluation of the relative efficacy of prasugrel versus ticagrelor using a stepped-wedge cluster randomized trial design.
Timeline
- Start
- 2022-02-01
- Primary completion
- 2025-08-31
- Completion
- 2025-08-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Prasugrel | Small molecule | 5 mg | Oral |
| Subject | Prasugrel | Small molecule | 10 mg | Oral |
| Comparator | Ticagrelor | Small molecule | 90 mg | Oral |