drugset / Trial / NCT05185843

A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRX) Administered to Adults With Familial Chylomicronemia Syndrome (FCS) Previously Treated With Volanesorsen

NCT05185843 ↗

Phase 3 Active not recruiting 24 enrolled Ionis Pharmaceuticals, Inc.
NaSingle-groupOpen-labelTreatment

Summary

The purpose of the study is to evaluate the safety, tolerability, pharmacokinetic (PK) and pharmacodynamic (PD) effects of olezarsen (formerly known as AKCEA -APOCIII-LRX) in participants with FCS previously treated with volanesorsen.

Timeline

Start
2022-02-25
Primary completion
2027-06
Completion
2027-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Olezarsen Antisense oligonucleotide — Subcutaneous