drugset / Trial / NCT05196373

Safety, Tolerability, Pharmacokinetics, Immunogenicity and Efficacy of STP705 in Adult Patients With Hypertrophic Scars

NCT05196373 ↗

Phase 1/2 Unknown 50 enrolled Sirnaomics
Non-randomizedSequentialOpen-labelTreatment

Summary

Adult patients with hypertrophic scars 30 Subjects in Dose Escalation 20 Subjects in Dose Expansion Intrascar injection of STP705 weekly for 4 weeks

Timeline

Start
2023-06
Primary completion
2024-12
Completion
2024-12

Drugs

EvaluationDrugModalityDoseRoute
Subject STP705 Small interfering RNA (siRNA) 10 ug Other
Subject STP705 Small interfering RNA (siRNA) 20 ug Other
Subject STP705 Small interfering RNA (siRNA) 40 ug Other
Subject STP705 Small interfering RNA (siRNA) 60 ug Other
Subject STP705 Small interfering RNA (siRNA) 80 ug Other
Subject STP705 Small interfering RNA (siRNA) 100 ug Other