drugset / Trial / NCT05199090

Study to Assess Safety, Tolerability and Efficacy of SC Administered MBL949 in Obese Participants With or Without T2DM

NCT05199090 ↗

Phase 2 Terminated 126 enrolled Novartis Pharmaceuticals
RandomizedSingle-groupDouble-blindTreatment

Summary

This was a multi-center, randomized, placebo-controlled, participant-and-investigator-blinded, sponsor open-label study in obese participants with or without Type 2 Diabetes Mellitus.

Timeline

Start
2022-02-10
Primary completion
2023-05-11
Completion
2023-05-11

Outcome

Outcome not reported

Stopped: “The tolerability to benefit ratio based on maximum weight loss observed was not considered favorable at the doses studied and the study was terminated early”

Drugs

EvaluationDrugModalityDoseRoute
Comparator MBL949 Unknown 2.2 mg Subcutaneous
Comparator MBL949 Unknown 4.5 mg Subcutaneous
Comparator MBL949 Unknown 7.5 mg Subcutaneous

Indications