drugset / Trial / NCT05204524
Temozolomide for Injection Combined With Epirubicin in First-line Treatment of Leiomyosarcoma
NaSingle-groupOpen-labelTreatment
Summary
This study is a single-center, prospective, one-arm clinical study, which is planned to be carried out in Cancer Hospital of Chinese Academy of Medical Sciences. The patients with locally advanced or metastatic leiomyosarcoma who are inoperable are enrolled, aiming at the effectiveness and safety of temozolomide for injection combined with epirubicin as the first-line treatment for advanced leiomyosarcoma.
Timeline
- Start
- 2021-08-27
- Primary completion
- 2022-08-27
- Completion
- 2023-08-27
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Epirubicin | Small molecule | 60 mg/m2 | — |
| Subject | Temozolomide | Small molecule | 200 mg | — |
| Subject | Temozolomide | Small molecule | 300 mg | — |