drugset / Trial / NCT05204524

Temozolomide for Injection Combined With Epirubicin in First-line Treatment of Leiomyosarcoma

NCT05204524

NaSingle-groupOpen-labelTreatment

Summary

This study is a single-center, prospective, one-arm clinical study, which is planned to be carried out in Cancer Hospital of Chinese Academy of Medical Sciences. The patients with locally advanced or metastatic leiomyosarcoma who are inoperable are enrolled, aiming at the effectiveness and safety of temozolomide for injection combined with epirubicin as the first-line treatment for advanced leiomyosarcoma.

Timeline

Start
2021-08-27
Primary completion
2022-08-27
Completion
2023-08-27

Drugs

EvaluationDrugModalityDoseRoute
Subject Epirubicin Small molecule 60 mg/m2
Subject Temozolomide Small molecule 200 mg
Subject Temozolomide Small molecule 300 mg

Indications