Application of Celiac Plexus Block in Postoperative Analgesia of Whipple Surgery

NCT05205720 ↗

Phase 4 Completed 78 enrolled Second Affiliated Hospital, School of Medicine, Zhejiang University

RandomizedParallel-groupDouble-blindTreatment

Summary

This subject intends to explore the value of intraoperative celiac plexus block in postoperative acute pain management and its promoting effect on patients' rapid recovery during Whipple surgery through a randomized controlled trial.

Timeline

Start: 2022-03-09
Primary completion: 2023-11-12
Completion: 2023-11-12

Outcome

Met primary endpoint

paper Group NB demonstrated significantly lower total opioid consumption within the first 72 h post-surgery than group GC PMID 40263988 ↗

paper 66 (18.8) mg vs. 88.9 (21.2) mg, respectively; P < 0.01 PMID 40263988 ↗

Publications

Li M, Fang L, Xing T, Wang C, Chen S, Yu S, Zhu J. A single-blind randomized controlled trial of celiac plexus block for analgesia after whipple surgery. BMC Anesthesiol. 2025 Apr 22;25(1):193. doi: 10.1186/s12871-025-03045-7.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Ropivacaine	Other / unclassified	0.5 %	Other
Subject	Ropivacaine	Other / unclassified	10 ml	Other

Indications

No indication recorded.