drugset / Trial / NCT05208242

Strong Albumin Solutions in Patients With Septic Shock

NCT05208242

RandomizedParallel-groupOpen-labelTreatment

Summary

Sepsis is an increasingly recognised burden to healthcare systems worldwide. Intravenous fluid therapy is a common first-line intervention recommended by international guidelines. Hyperoncotic preparations of human albumin solution are widely available, but their efficacy has yet to be proven. This randomised feasibility trial will test whether it is feasible to administer hyperoncotic albumin solutions as both fluid resuscitation and as a regular supplement in patients with early septic shock.

Timeline

Start
2023-11-10
Primary completion
2025-04-05
Completion
2026-01-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Albumin Protein / enzyme biologic 20 %