drugset / Trial / NCT05212246

Basal Cell Carcinoma Chemoprevention Trial

NCT05212246

Phase 3 Not yet recruiting 1630 enrolled VA Office of Research and Development
RandomizedParallel-groupQuadruple-blindPrevention

Summary

This is an intent-to-treat, parallel design, multicenter randomized trial and the primary intervention is a double-blind comparison of Imiquimod (IMQ) vs. placebo cream for preventing basal cell carcinoma (BCC) of the skin on the face at one year and over 3 years after therapy. Participants will apply the IMQ or placebo cream to the face daily at bedtime for 12 weeks. This study will recruit 1630 Veterans at high risk of BCC from 17 VA medical centers.

Timeline

Start
2026-08-03
Primary completion
2032-08-03
Completion
2032-08-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Imiquimod Other / unclassified 5 % Topical

Indications