drugset / Trial / NCT05213507

Inhaled Amikacin in Preventing AECOPD

NCT05213507

Phase 3 Unknown 136 enrolled Shanghai Zhongshan Hospital
RandomizedParallel-groupOpen-labelPrevention

Summary

The underlying bacterial colonization in lower respiratory tract (LRT) of COPD patients may be related to acute exacerbation of COPD (AECOPD) and disease progression. However, there is a lack of strong evidence on the effect of LRT bacterial decolonization on COPD. This study was designed to confirm the prophylactic effect of decolonization of LRT bacteria on AECOPD and establish a novel prophylactic therapy for sable COPD.

Timeline

Start
2022-03
Primary completion
2023-12
Completion
2023-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Amikacin Small molecule 0.4 g Inhaled