drugset / Trial / NCT05213585

Treatment of Ocular Demodex Infestation With Topical Ivermectin Cream 1%

NCT05213585

Phase 1 Unknown 20 enrolled Helm Vision Group
RandomizedParallel-groupSingle-blindTreatment

Summary

Patients with Demodex infestation of the eyelids will have the sleeves from both eyes cleaned off with microblepharoexfoliation. Afterwards, one eye will be randomly selected for treatment with topical ivermectin 1% cream. The treatment will be repeated on that eye 2 weeks later. Afterwards, the patients will present monthly for photographs of the eyelashes. The photographs will be reviewed by an ophthalmologist outside of our institution who will be blind to which eye was treated and independently grade the amount of sleeves in each eye. The follow-up will be for 6 months after the second treatment.

Timeline

Start
2021-08-24
Primary completion
2022-05-30
Completion
2022-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Ivermectin Small molecule 1 % Topical

Indications

No indication recorded.