drugset / Trial / NCT05219578
RTX-224 Monotherapy in Patients With Solid Tumors
Non-randomizedSequentialOpen-labelTreatment
Summary
This is an open-label, multidose, first-in-human (FIH), Phase 1/2 study of RTX-224 for the treatment of patients with relapsed or refractory (R/R), or locally advanced solid tumors.
Timeline
- Start
- 2022-01-12
- Primary completion
- 2022-11-30
- Completion
- 2022-11-30
Outcome
Outcome not reported
Stopped: “The Sponsor terminated study after dosing 2 dose groups (7 pts) and closed trial on 11/30/22. RTX-224 was well-tolerated with no DLTs, no related deaths, SAEs or Gr. 3/4 AEs and cleared rapidly (w/in 10 min).”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | RTX-224 | Unknown | — | Intravenous |