drugset / Trial / NCT05219578

RTX-224 Monotherapy in Patients With Solid Tumors

NCT05219578 ↗

Phase 1/2 Terminated 7 enrolled Rubius Therapeutics
Non-randomizedSequentialOpen-labelTreatment

Summary

This is an open-label, multidose, first-in-human (FIH), Phase 1/2 study of RTX-224 for the treatment of patients with relapsed or refractory (R/R), or locally advanced solid tumors.

Timeline

Start
2022-01-12
Primary completion
2022-11-30
Completion
2022-11-30

Outcome

Outcome not reported

Stopped: “The Sponsor terminated study after dosing 2 dose groups (7 pts) and closed trial on 11/30/22. RTX-224 was well-tolerated with no DLTs, no related deaths, SAEs or Gr. 3/4 AEs and cleared rapidly (w/in 10 min).”

Drugs

EvaluationDrugModalityDoseRoute
Subject RTX-224 Unknown — Intravenous