drugset / Trial / NCT05221905

Effects of Inorganic Nitrate and Intensity of Exercise on Cardiovascular Health in Post-Menopausal Females

NCT05221905 ↗

Phase 1 Completed 24 enrolled University of Virginia
RandomizedParallel-groupDouble-blindBasic science

Summary

Post-menopausal females experience elevated cardiovascular disease risk (CVD), compared to premenopausal females and age-matched males. Current exercise guidelines appear inadequate to ameliorate this increased risk and higher intensity exercise may be necessary. Oral inorganic nitrate supplementation enhances both exercise performance and CVD risk profile in several clinical conditions. However, the effects of this intervention in post-menopausal females is unexplored.

Timeline

Start
2021-11-01
Primary completion
2023-04-01
Completion
2023-04-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Beet It Sport Unknown 400 mg Oral