drugset / Trial / NCT05222737

Quantitation of Bacteria Associated With Severe Periodontitis by Real -Time PCR Following Application of Diode Laser

NCT05222737

Phase 2/3 Completed 50 enrolled Alexandria University
RandomizedParallel-groupDouble-blindTreatment

Summary

1. Primary objective To measure the gingival crevicular levels of A.actinomycetemcomitans and P.gingivalis after intra-pocket application of diode laser in severe periodontitis (stage 3 grade C) patients. 2. Secondary objective To compare the levels of the same microorganisms as in cases of diode laser therapy to those after conventional treatment with systemic antibiotic administration in severe periodontitis (stage 3 grade C) patients. 3. to measure clinical parameters probing depth,attachment loss and mobility grade

Timeline

Start
2021-01-01
Primary completion
2021-09-01
Completion
2021-12-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Metronidazole Small molecule
Comparator Spiramycin Small molecule

Indications