Personalized Immune Cell Therapy Targeting Neoantigen of Malignant Solid Tumors

Summary

This single center, single arm and prospective study aimed to establish gene mutation database and select the neoantigens in patients with advanced malignant melanoma, bladder cancer and colorectal cancer. Then, we intended to explore the safety and efficacy of individual tumor antigen-sensitized DC vaccine and their sensitized T cells in these solid cancers.

Timeline

Start

2022-03-01

Primary completion

2023-06-01

Completion

2023-12-02

Drugs

Indications