drugset / Trial / NCT05239546

Single Arm Study of Neoadjuvant Dostarlimab in Stage II and III Deficient Mismatch Repair Colon Cancers

NCT05239546

Phase 2 Recruiting 25 enrolled University of Iowa
NaSingle-groupOpen-labelTreatment

Summary

This is a Phase II, single arm study looking at the rate of major clinical response and non-operative management in Stage II and III colon cancer after 18 weeks (up to 6 cycles) of neoadjuvant dostarlimab.

Timeline

Start
2023-03-24
Primary completion
2028-06-30
Completion
2029-06-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Dostarlimab Monoclonal antibody 1000 mg Intravenous

Indications