PSLT Compared to Prostaglandin Analogue Eye Drops

Summary

This study aims to compare the efficacy of PSLT and the topical use of prostaglandin-like hypotensive eye drops in the treatment of ocular hypertensive or glaucomatous patients in decreasing intraocular pressure and measuring changes in functional, structural and biomechanical parameters evaluated by computerized perimetry and optical coherence tomography (OCT) related to pressure change resulting from treatments

Timeline

Start

2021-09-01

Primary completion

2022-12-20

Completion

2022-12-20

Publications

• de Almeida RCMC, Lindenmeyer RL, Lavinsky F, Lavinsky D, Picetti E, da Silva MO, Marinho DR, Moreira TS, Silveira VA, Leivas L, Meireles LDC, Pakter HM. Pascal selective laser trabeculoplasty (PSLT) in the treatment of ocular hypertension and open-angle glaucoma compared to travoprost eye drops: A non-inferiority clinical trial. PLoS One. 2026 Jul 8;21(7):e0350897. doi: 10.1371/journal.pone.0350897. eCollection 2026.

Drugs

Indications