Psilocybin for Opioid Use Disorder in Patients on Methadone Maintenance With Ongoing Opioid Use

Summary

This study will investigate whether psilocybin administered under supportive conditions can reduce illicit opioid use and improve quality of life in individuals with Opioid Use Disorder (OUD) in Methadone Maintenance Treatment (MMT) who are concurrently using other opioids illicitly.

Timeline

Start

2023-12

Primary completion

2024-02

Completion

2024-12

Outcome

Outcome not reported

Stopped (Business): “Lack of funding”

Publications

• Nicholas CR, Horton DM, Malicki J, Baltes A, Hutson PR, Brown RT. Psilocybin for Opioid Use Disorder in Two Adults Stabilized on Buprenorphine: A Technical Report on Study Modifications and Preliminary Findings. Psychedelic Med (New Rochelle). 2023 Dec 13;1(4):253-261. doi: 10.1089/psymed.2023.0012. eCollection 2023 Dec.

Drugs

Indications