drugset / Trial / NCT05242822

A Study to Evaluate KIN-3248 in Participants With Advanced Tumors Harboring FGFR2 and//or FGFR3 Gene Alterations

NCT05242822 ↗

Phase 1 Terminated 54 enrolled Kinnate Biopharma
Non-randomizedSequentialOpen-labelTreatment

Summary

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary efficacy of KIN-3248, an oral small molecule FGFR inhibitor, in adults with advanced tumors harboring FGFR2 and/or FGFR3 gene alterations.

Timeline

Start
2022-03-29
Primary completion
2024-10-03
Completion
2024-10-03

Outcome

Outcome not reported

Stopped (Enrollment): “Due to a change in the Sponsor's corporate strategy the study was terminated early by the Sponsor prior to enrollment into the dose expansion part of the study (Part B).”

Drugs

EvaluationDrugModalityDoseRoute
Subject KIN-3248 Small molecule — Oral