drugset / Trial / NCT05243199

Sacubitril/Valsartan for CKD5 Stage Dialysis Patients

NCT05243199

Phase 4 Completed 330 enrolled Ruijin Hospital
RandomizedParallel-groupOpen-labelTreatment

Summary

Hemodialysis or peritoneal dialysis CKD5 patients were randomly divided into Sacubitril/Valsartan and irbesartan treatment groups. Comparing the blood pressure, survival rates, the cardiac function, renal function,and adverse reactions of two groups, to evaluate whether the efficacy and safety of Sacubitril/Valsartan in the treatment of patients with CKD dialysis combined with heart failure is superior to that of irbesartan.

Timeline

Start
2020-08-01
Primary completion
2023-03-01
Completion
2023-03-08

Drugs

EvaluationDrugModalityDoseRoute
Comparator Irbesartan Small molecule 150 mg
Subject Sacubitril/Valsartan Unknown 100 mg