drugset / Trial / NCT05243199
Sacubitril/Valsartan for CKD5 Stage Dialysis Patients
RandomizedParallel-groupOpen-labelTreatment
Summary
Hemodialysis or peritoneal dialysis CKD5 patients were randomly divided into Sacubitril/Valsartan and irbesartan treatment groups. Comparing the blood pressure, survival rates, the cardiac function, renal function,and adverse reactions of two groups, to evaluate whether the efficacy and safety of Sacubitril/Valsartan in the treatment of patients with CKD dialysis combined with heart failure is superior to that of irbesartan.
Timeline
- Start
- 2020-08-01
- Primary completion
- 2023-03-01
- Completion
- 2023-03-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Irbesartan | Small molecule | 150 mg | — |
| Subject | Sacubitril/Valsartan | Unknown | 100 mg | — |