Statin InTensity to Prevent Coronary Artery Vasculopathy After Heart Transplantation

Summary

The investigator's propose to conduct an open-label randomized controlled trial to determine if higher intensity statin (HS) can reduce CAV in comparison to lower intensity statin (LS) after HT. All consecutive patients that meet eligibility criteria will be approached for participation. After heart transplantation, participants (n=70) will be randomized in a 1:1 manner to either HS or LS. Study participation will be for 2 years from the time of randomization. Study outcomes will be compared by research staff blinded to statin group assignment.

Timeline

Start

2025-01

Primary completion

2030-06

Completion

2030-06

Drugs

Indications