Effect of Colchicine on the Progression of Aortic Valve Stenosis - A Pilot Study

Summary

COPAS pilot is a pilot single center double blinded randomized study to determine the effect of targeted anti-inflammation therapy using colchicine, on valvular calcification activity using imaging, i.e. aortic valvular NaF uptake. The current proposal uses a randomized design to evaluate the effect of colchicine vs. placebo on valvular calcification activity over 6 months measured using NaF PET

Timeline

Start

2022-07-01

Primary completion

2024-07-31

Completion

2025-01-20

Drugs

Indications