drugset / Trial / NCT05254652
The Clinical Effect of Pregabalin on Neuropathic Pain in Central Sensitized Patients After Total Knee Arthroplasty
RandomizedParallel-groupOpen-labelTreatment
Summary
In this study, patients scheduled to undergo total knee arthroplasty (TKA) will be screened through a survey for patients with central sensitivity and patients with neuropathic pain as preoperative evaluation. It is designed to evaluate the effectiveness of pregabalin with the decision to prescribe duloxetine by dividing patient groups according to central sensitization and neuropathic pain.
Timeline
- Start
- 2022-05
- Primary completion
- 2023-05
- Completion
- 2023-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Pregabalin | Small molecule | 150 mg | — |
| Background | Duloxetine | Small molecule | 30 mg | — |