A Trial to Compare the Ovarian Response of REKOVELLE and GONAL-F in Conventional Dosing in Women Undergoing Controlled Ovarian Stimulation

Summary

Hormone preparations like REKOVELLE and GONAL-F are used to make the body produce multiple egg sacs, allowing more eggs to be collected from women undergoing infertility treatment. The main purpose of this trial is to see how many eggs are produced with a starting dose of 15 µg REKOVELLE compared to a starting dose of 225 IU GONAL-F. This research is intended to provide more knowledge about REKOVELLE, including the doses given in the trial.

Timeline

Start

2022-07-15

Primary completion

2024-04-16

Completion

2024-04-16

Publications

• Bernabeu A, Zajc P, Garcia Sanchez M, Agrawal R, Papaleo E, Jirecek S, Mogelmose S, Jepsen IE, Lobo R. Ovarian stimulation with follitropin delta for in vitro fertilization: a multicentre, randomized, assessor-blind comparison with follitropin alfa using conventional dosing regimens (ADAPT-1 trial). Hum Reprod. 2025 Sep 1;40(9):1660-1670. doi: 10.1093/humrep/deaf119.

Drugs

Indications