drugset / Trial / NCT05263674
Fast Acute Sedation at Intensive Care vs. High-dose i.v. Anti-seizure Medication for Treatment of Non-convulsive Status Epilepticus (FAST-trial)
Phase 3
Recruiting
140 enrolled
University of Southern Denmark
Aarhus University Hospital · collabCopenhagen University Hospital, Denmark · collabUniversity Hospital of Zealand · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
This open-label, randomized multicenter trial aims at clarifying the standard of care of patients with non-convulsive status epilepticus not responding to treatment with benzodiazepines and at least one high-dose intra venous anti-seizure medication.
Timeline
- Start
- 2022-02-07
- Primary completion
- 2027-12-31
- Completion
- 2028-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Propofol | Small molecule | 5 mg/kg | — |
| Subject | Propofol | Small molecule | 10 mg/kg | — |
| Background | Midazolam | Small molecule | 0.1 mg/kg | — |